The Celli Lab

University of Massachusetts Boston
Department of Physics

Publications

For an up-to-date listing and citations, see the lab's Google Scholar profile.

2026

  1. Ferro AP, Mensah SK, Liu YR, de Oliveira Guirro EC, Celli JP. Photobiomodulation pre-treatment enhances ALA-induced PpIX accumulation and photodynamic therapy response in oral squamous cell carcinoma cells in cell culture. Photodiagnosis and Photodynamic Therapy. 2026 Mar 12:105433.

2025

  1. Liboy C, Khan S, Song B, Vega D, Saad MA, Liang R, Hasan T, Celli JP. Imaging protoporphyrin IX photoproduct accumulation as a dosimetry reporter for monitoring photodynamic therapy of oral cancer. Journal of Biomedical Optics. 2025 Dec 1;30(S3):S34114.
  2. Khan S, Song B, Saad MA, Boodhoo D, Farias S, Trzcinski JM, Li S, Lilge L, Pogue BW, Liang R, Hasan T. Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy. Biophotonics Discovery. 2025 Oct 1;2(4):042305.
  3. Celli JP, Khan S. "Photodynamic Therapy for Targeted Treatment of Oral Cancers." (2025), Encyclopedia of Green Chemistry, Elsevier. doi:10.1016/B978-0-443-15742-4.00040-5

2024

  1. Liu Y, Mensah SK, Farias S, Khan S, Hasan T, Celli JP. Efficacy of photodynamic therapy using 5-aminolevulinic acid-induced photosensitization is enhanced in pancreatic cancer cells with acquired drug resistance. Photodiagnosis and Photodynamic Therapy. 2024 Dec 1;50:104362.
  2. Struth E, Labaf M, Karimnia V, Liu Y, Cramer G, Dahl JB, Slack FJ, Zarringhalam K, Celli JP. Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models. Scientific Reports. 2024 Sep 5;14(1):20698.
  3. Obaid G, Celli JP, Broekgaarden M, Bulin AL, Uusimaa P, Pogue B, Hasan T, Huang HC. Engineering photodynamics for treatment, priming and imaging. Nature Reviews Bioengineering. 2024 Sep;2(9):752-69.
  4. Ferro AP, de Jesus Guirro RR, Ferraresi C, Celli J, Orellana MD, de Santis GC, Junior JA, de Oliveira Guirro EC. Influence of different photobiomodulation parameters on multi-potent adipose tissue mesenchymal cells in vitro. Photobiomodulation, Photomedicine, and Laser Surgery. 2024 Mar;42(3):200-7.

2023

  1. Khan S, Song B, Mallidi S, Li S, Liu H, Bilal Hussain MA, Siddiqui S, Khan AP, Akhtar K, Siddiqui SA, Hasan SA. Clinical assessment of a low-cost, hand-held, smartphone-attached intraoral imaging probe for 5-aminolevulinic acid photodynamic therapy monitoring and guidance. Journal of Biomedical Optics. 2023 Aug 1;28(8):082809.
  2. Nadeem M, Pervez L, Khan AM, Burton RA, Ullah S, Nadhman A, Celli J. Microbial-mediated synthesis of gold nanoparticles - current insights and future vistas. Gold Bulletin. 2023 Jun;56(2):69-81.
  3. Dick M, Jamal H, Liu YR, Celli JP, Lilge L. On the need for standardized reporting of photophysical parameters of in vitro photodynamic therapy studies. Photodiagnosis and Photodynamic Therapy. 2023 Mar 1;41:103263.
  4. Karimnia V, Stanley ME, Fitzgerald CT, Rizvi I, Slack FJ, Celli JP. Photodynamic stromal depletion enhances therapeutic nanoparticle delivery in 3D pancreatic ductal adenocarcinoma tumor models. Photochemistry and Photobiology. 2023 Jan;99(1):120-31.

2022

  1. Khan AM, Pervez L, Celli J, Khattak M, Ullah M, Shah Z, Khan MM, Nadeem M, Faisal S, Nadhman A. Photokilling of waterborne-resistant pathogenic bacteria using cobalt-doped zinc oxide doped on reduced graphene oxide nanoparticles. Journal of Innovative Optical Health Sciences. 2022 Jul 9;15(04):2240003.
  2. Siddiqui SA, Siddiqui S, Hussain MB, Khan S, Liu H, Akhtar K, Hasan SA, Ahmed I, Mallidi S, Khan AP, Cuckov F. Clinical evaluation of a mobile, low-cost system for fluorescence guided photodynamic therapy of early oral cancer in India. Photodiagnosis and Photodynamic Therapy. 2022 Jun 1;38:102843.
  3. Girasol CE, Braz GD, Bachmann L, Celli J, Guirro RR. Laser light sources for photobiomodulation: The role of power and beam characterization in treatment accuracy and reliability. PLoS One. 2022 Mar 30;17(3):e0266193.
  4. Petrovic LZ, Oumano M, Hanlon J, Arnoldussen M, Koruga I, Yasmin-Karim S, Ngwa W, Celli J. Image-Based Quantification of Gold Nanoparticle Uptake and Localization in 3D Tumor Models to Inform Radiosensitization Schedule. Pharmaceutics. 2022 Mar 18;14(3):667.
  5. Petrovic LZ, Karimnia V, Mallidi S, Celli JP. Plasmonic Nanoparticles for Enhancement of Image-Guided Phototherapy. In World Scientific Reference on Plasmonic Nanomaterials: Principles, Design and Bio-applications: Volume 4: Nanoparticle-Cell Interactions 2022 (pp. 181-204).

2021

  1. Nadeem M, Khan R, Shah N, Bangash IR, Abbasi BH, Hano C, Liu C, Ullah S, Hashmi SS, Nadhman A, Celli J. A review of microbial mediated iron nanoparticles (IONPs) and its biomedical applications. Nanomaterials. 2021 Dec 31;12(1):130.
  2. Karimnia V, Slack FJ, Celli JP. Photodynamic therapy for pancreatic ductal adenocarcinoma. Cancers. 2021 Aug 28;13(17):4354.
  3. Karimnia V, Rizvi I, Slack FJ, Celli JP. Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models. Photochemistry and Photobiology. 2021;97(2):416-426.

2020

  1. Khan S, Hussain MAB, Khan AP, Liu H, Siddiqui S, Mallidi S, Alacron PL, Daly L, Rudd G, Cuckov F, Hopper C, Bown SG, Akhtar K, Hasan SA, Siddiqui SA, Hasan T, Celli JP. Clinical evaluation of smartphone-based fluorescence imaging for guidance and monitoring of ALA-PDT treatment of early oral cancer. Journal of Biomedical Optics. 2020;25(6):063813.
  2. Samkoe KS, Celli JP, Zhu TC. Special Section Guest Editorial: Photodynamic Therapy. Journal of Biomedical Optics. 2020;25(6):063801.
  3. Nath S, Pigula M, Khan AP, Hanna W, Ruhi MK, Dehkordy FM, Pushpavanam K, Rege K, Moore K, Tsujita Y, Conrad C, Inci F, Del Carmen MG, Franco W, Celli JP, Demirci U, Hasan T, Huang HC, Rizvi I. Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress. Journal of Clinical Medicine. 2020;9(4):924.
  4. Sorrin AJ, Ruhi MK, Ferlic NA, Karimnia V, Polacheck WJ, Celli JP, Huang HC, Rizvi I. Photodynamic therapy and the biophysics of the tumor microenvironment. Photochemistry and Photobiology. 2020;96(2):232-259.
  5. Jafari R, Cramer GM, Celli JP. Modulation of Extracellular Matrix Rigidity Via Riboflavin-mediated Photocrosslinking Regulates Invasive Motility and Treatment Response in a 3D Pancreatic Tumor Model. Photochemistry and Photobiology. 2020;96(2):365-372.

2019

  1. Liu H, Daly L, Rudd G, Khan AP, Mallidi S, Liu Y, Cuckov F, Hasan T, Celli JP. Development and evaluation of a low-cost, portable, LED-based device for PDT treatment of early-stage oral cancer in resource-limited settings. Lasers in Surgery and Medicine. 2019;51(4):345-351.
  2. Mallidi S, Khan AP, Liu H, Daly L, Rudd G, Leon P, Khan S, Hussain BMA, Hasan SA, Siddique SA, Akhtar K, August M, Troulis M, Cuckov F, Celli JP, Hasan T. Platform for ergonomic intraoral photodynamic therapy using low-cost, modular 3D-printed components: design, comfort and clinical evaluation. Scientific Reports. 2019;9(1):1-8.
  3. Kumar N, Cramer GM, Zamani Dahaj SA, Sundaram B, Celli JP, Kulkarni RV. Stochastic modeling of phenotypic switching and chemoresistance in cancer cell populations. Scientific Reports. 2019;9:10845.
  4. Rodriguez-Quijada C, de Puig H, Sanchez-Purra M, Yelleswarapu C, Evans JJ, Celli JP, Hamad-Schifferli K. Protease Degradation of Protein Coronas and Its Impact on Cancer Cells and Drug Payload Release. ACS Applied Materials & Interfaces. 2019;11(16):14588-14596.

2018

  1. Leon P, Rudd G, Daly L, Liu H, Celli JP, Hasan T, Cuckov F. Development of a portable intraoral camera and a smartphone application for oral cancer PDT treatment guidance and monitoring. 2018 IEEE Biomedical Circuits and Systems Conference (BioCAS), 1-4.
  2. Chen H, Yeh TH, He J, Zhang C, Abbel R, Hamblin MR, Huang Y, Lanzafame RJ, Stadler I, Celli J, Liu SW, Wu ST, Dong Y. Flexible quantum dot light-emitting devices for targeted photomedical applications. Journal of the Society for Information Display. 2018;26(5):296-303.
  3. Broekgaarden M, Rizvi I, Bulin AL, Petrovic L, Goldschmidt R, Massodi I, Celli JP, Hasan T. Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids. Oncotarget. 2018;9(16):13009.

2017

  1. Jones DP, Hanna W, Cramer GM, Celli JP. In situ measurement of ECM rheology and microheterogeneity in embedded and overlaid 3D pancreatic tumor stroma co-cultures via passive particle tracking. Journal of Innovative Optical Health Sciences. 2017;1742003.
  2. Chen H, He J, Lanzafame R, Stadler I, El Hamidi H, Liu H, Celli J, Hamblin MR, Huang Y, Oakley E, Shafirstein G, Chung HK, Wu ST, Dong Y. Quantum dot light emitting devices for photomedical applications. Journal of the Society for Information Display. 2017;25(3):177-184.
  3. Celli JP, Anderson MD. Cancer Biophysics. Elsevier Reference Module Series (2017).
  4. Daly L, Rudd G, Liu H, Leon P, Celli J, Cuckov F. Embedded system for a battery-operated LED-based photodynamic therapy device for treatment of early-stage oral cancers in resource-limited settings. 2017 2nd International Conference on Bio-engineering for Smart Technologies (BioSMART) (2017) 1-4.
  5. Cramer GM, Jones DP, El Hamidi H, Celli JP. ECM Composition and Rheology Regulate Growth, Motility and Response to Photodynamic Therapy in 3D Models of Pancreatic Ductal Adenocarcinoma. Molecular Cancer Research. 2017;15(1):1-25.

2016

  1. Ouyang Z, Mainali M, Sinha N, Strack G, Altundal Y, Hao Y, Winningham T, Sajo E, Celli JP, Ngwa W. Potential of using cerium oxide nanoparticles for protecting healthy tissue during Accelerated Partial Breast Irradiation. Physica Medica. 2016;32(4):631-635.
  2. Liu H, Celli JP. Looking out the optical window: Physical principles and instrumentation for imaging in photodynamic therapy. In Imaging and Photodynamic Therapy by Taylor and Francis. In Press.
  3. Cramer GM, El Hamidi H, Jafari S, Jones DP, Celli JP. Extracellular matrix composition and rigidity regulate invasive behavior and response to PDT in 3D pancreatic tumor models. Proc SPIE 2016, 96940J.
  4. Liu H, Rudd G, Daly L, Hempstead J, Liu Y, Khan AP, Mallidi S, Thomas R, Rizvi I, Arnason S, Cuckov F, Hasan T, Celli JP. Development of low-cost devices for image-guided photodynamic therapy treatment of oral cancer in global health settings. Proc SPIE 2016, 96940C.

2015

  1. Hempstead J, Jones DP, Ziouche A, Cramer G, Rizvi I, Arnason S, Hasan T, Celli JP. Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models. Scientific Reports. 2015;5:10093.
  2. Mallidi S, Mai Z, Rizvi I, Hempstead J, Arnason S, Celli JP, Hasan T. In vivo evaluation of battery-operated LED based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints. Journal of Biomedical Optics. 2015;20(4):048003.
  3. Jones DP, Hanna W, Celli JP. Mapping dynamic mechanical remodeling in 3D tumor models via particle tracking microrheology. Proc SPIE 2015, 93270L.
  4. Rizvi I, Gudejko H, Briars E, Khan S, Chiang C, El-Hamidi H, Celli JP, Hasan T. 3D Cancer Models on Hydrogels. In Gels Handbook Volume 1: Fundamentals, Properties and Applications. Editor S. Majd. World Scientific Publishing 2015.

2014

  1. Li Y, Petrovic L, La J, Celli JP, Yelleswarapu CS. Digital holographic microscopy for longitudinal volumetric imaging of growth and treatment response in 3D tumor models. Journal of Biomedical Optics. 2014;19(11):116001.
  2. Jones DP, Hanna W, El-Hamidi H, Celli JP. Longitudinal quantification of local mechanical changes in 3D tumor models using particle-tracking microrheology. J Vis Exp. (88), e51302, doi:10.3791/51302 (2014).
  3. Li Y, Petrovic L, Celli JP, Yelleswarapu CS. Digital Holographic Microscopy (DHM) for imaging growth and treatment response in 3D tumor models. Proc SPIE 2014, 8957-3.
  4. Celli JP, Rizvi I, Blanden AR, Massodi I, Glidden MD, Pogue BW, Hasan T. An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models. Scientific Reports. 2014;4:3751.

2013

  1. Anbil S, Rizvi I, Celli JP, Alagic N, Pogue BW, Hasan T. Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer. Journal of Biomedical Optics. 2013;18(9):098004.
  2. Celli JP, Petrovic L, Massodi I, Rizvi I, Hasan T. Overcoming therapeutic resistance in pancreatic cancer is not a simple mix of PDT and chemotherapy: Evaluation of PDT-chemotherapy combinations in 3D tumor models. Proc SPIE 2013, 8568-0R.
  3. Bansil R, Celli JP, Hardcastle JM, Turner BS. The influence of mucus microstructure and rheology in H. pylori infection. Frontiers in Immunology. 2013;4:310, doi:10.3389/fimmu.2013.00310.
  4. Rizvi I, Gurkan UA, Tasoglu S, Alagic N, Celli JP, Mensah LB, Mai Z, Demirci U, Hasan T. Flow Induces a Motile and Aggressive Phenotype in 3D Ovarian Cancer Nodules via Increased EMT, Activated EGFR and Decreased E-Cadherin. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(22):E1974-E1983.
  5. Rizvi I, Anbil SA, Alagic N, Celli JP, Zheng LZ, Palanisami A, Glidden MD, Pogue BW, Hasan T. PDT Dose Parameters Impact Tumoricidal Durability and Cell Death Pathways in a 3D Ovarian Cancer Model. Photochemistry and Photobiology. 2013;89(4):942-952.

2012

  1. Glidden MD, Celli JP, Massodi I, Hasan T. Image-based quantification of photosensitizer uptake, localization and photobleaching in a 3D tumor model for optimization of PDT parameters. Theranostics. 2012;2(9):827-839.
  2. Celli JP. Stromal interactions as regulators of tumor growth and therapeutic response: A potential target for photodynamic therapy? Israel Journal of Chemistry. 2012;52:757-766.
  3. Glidden MD, Massodi I, Rizvi I, Celli JP, Hasan T. Probing tumor-stroma interactions and response to photodynamic therapy in a 3D pancreatic cancer-fibroblast co-culture model. Proc SPIE 2012, 8210-05.

2011

  1. Xu F, Celli JP, Rizvi I, Moon S, Hasan T, Demirci U. A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform. Biotechnology Journal. 2011;6, doi:10.1002/biot.201000340.
  2. Celli JP, Solban N, Liang A, Pereira SP, Hasan T. Verteporfin-based photodynamic therapy overcomes gemcitabine insensitivity in a panel of pancreatic cancer cell lines. Lasers in Surgery and Medicine. 2011;43(7):565-574.
  3. Evans CL, Abu-Yousif AO, Park YJ, Klein OJ, Celli JP, Rizvi I, Zheng X, Hasan T. Killing Hypoxic Cell Populations in a 3D Tumor Model with EtNBS-PDT. PLoS One. 2011;6(8):e23434.
  4. Celli JP, Rizvi I, Blanden A, Abu-Yousif AO, Spring B, Hasan T. Biologically-relevant 3D tumor arrays: Imaging-based methods for quantification of reproducible growth and analysis of treatment response. Proc SPIE 2011, 7886-08.
  5. Rizvi I, Celli JP, Xu F, Evans CL, Abu-Yousif AO, Muzikansky A, Elrington SA, Pogue BW, Finkelstein DM, Demirci U, Hasan T. Biologically-relevant 3D tumor arrays: Treatment response and the importance of stromal partners. Proc SPIE 2011, 7886-09.
  6. Celli JP, Rizvi I, Blanden A, Evans C, Abu-Yousif A, Spring B, Muzikansky A, Pogue B, Finkelstein D, Hasan T. Imaging Enabled Platforms for Development of Therapeutics. Proc SPIE 2011, 7910-1.

2010

  1. Celli JP, Spring BQ, Rizvi I, Evans CL, Samkoe KS, Verma S, Pogue BW, Hasan T. Imaging and Photodynamic Therapy: Mechanisms, Monitoring and Optimization. Chemical Reviews. 2010;110(5):2795-2838. PMID: 20353192.
  2. Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T. Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a 3D model for ovarian cancer. Journal of Biomedical Optics. 2010;15(5):051603.
  3. Rahmanzadeh R, Rai P, Celli JP, Rizvi I, Baron-Luehr B, Gerdes J, Hasan T. Ki-67 as a molecular target for therapy in an in vitro 3D model for ovarian cancer. Cancer Research. 2010;70(22):9234-42.
  4. Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue B, Finkelstein D, Hasan T. Carboplatin efficacy enhanced synergistically by Photodynamic Therapy in a 3D model of micrometastatic ovarian cancer. Cancer Research. 2010;70(22):9319-28.
  5. Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T. 3D ovarian cancer models: imaging and therapeutic combinations. Proc SPIE 2010, 7551-17.

2009

  1. Celli JP, Turner BS, Afdhal NH, Keates S, Ghiran I, Kelly C, Ewoldt RH, McKinley GH, So P, Erramilli S, Bansil R. Helicobacter pylori moves through mucus by reducing mucin viscoelasticity. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(34):14321-14326. (Featured as a Research Highlight in Nature Reviews Microbiology 2009;7(10):689.)
  2. Zhong W, Celli JP, Rizvi I, Mai Z, Spring B, Yun SH, Hasan T. In vivo high resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring. British Journal of Cancer. 2009;101:2015-2022.
  3. Abu-Yousif AO, Rizvi I, Evans CL, Celli JP, Hasan T. PuraMatrix Encapsulation of Cancer Cells. Journal of Visualized Experiments. 2009;34.
  4. Evans CL, Rizvi I, Celli JP, Abu-Yousif AO, de Boer JF, Hasan T. Visualizing photodynamic therapy response with time-lapse OCT in an in vitro model of metastatic ovarian cancer. Proc SPIE 2009, 7551-18.
  5. Spring BQ, Celli JP, Evans CL, Zhong W, Rizvi I, Mai Z, Mertz J, Yun SH, Hasan T. Intravital fiber-optic fluorescence imaging for monitoring ovarian carcinoma progression and treatment response. Proc SPIE 2009, 7380, 73800L.

2007 and Earlier

  1. Celli JP, Turner BS, Afdhal NH, Ewoldt RH, McKinley GH, Bansil R, Erramilli S. Rheology of Gastric Mucin Exhibits a pH-Dependent Sol-Gel Transition. Biomacromolecules. 2007;8(5):1580-86.
  2. Hicks RS, Decowski P, Arroyo C, Breuer M, Celli JP, Chudakov E, Kumar KS, Olson M, Peterson GA, Pope K, Ricci J, Savage J, Souder PA. Flux profile scanners for scattered high-energy electrons. Nuclear Instruments and Methods in Physics Research Section A. 2005;553(3):470-482.
  3. Celli JP, Gregor BF, Turner BS, Afdhal NH, Bansil R, Erramilli S. Viscoelastic Properties and Dynamics of Porcine Gastric Mucin. Biomacromolecules. 2005;6(3):1329-33.
  4. Bansil R, Celli JP, Chasan B, Erramilli S, Hong Z, Afdhal NH, Bhaskar KR, Turner BS. pH-dependent Gelation of Gastric Mucin. Mat Res Soc. 2005; Symp J Proc. Vol. 897E.