The Celli Lab

University of Massachusetts Boston
Department of Physics

Our lab is motivated by an appreciation for the wide variety of challenges in cancer research that can be overcome from the application of physics-based methods and analysis. While great advances have clearly resulted from the study of molecular/cellular biology and genetics of cancer, certain determinants of tumor growth behavior and therapeutic response point directly to the application of concepts and techniques from the physical sciences. In this context, a major focus of our work is the development of treatment strategies using photodynamic therapy (PDT), a light-based therapeutic modality in which wavelength-specific activation of a photosensitizing chemical can be used to impart selective cytotoxicity to malignant tissues.

To learn more about our research interests, recent publications and more, please follow the links to the left.

Jonathan P. Celli, Ph.D — Principal Investigator
Principal Investigator
Professor
Jonathan P. Celli, Ph.D

Research Areas

Photodynamic Therapy

Developing light-activated treatments that selectively target tumor cells while sparing healthy tissue.

Optical Imaging

Using advanced imaging techniques to monitor treatment response and tumor microenvironments in real time.

Tumor Biophysics

Quantifying the physical properties of cancer to inform more effective combination therapies.